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& Horton, D

The reasons for a delayed diagnosis vary markedly between countries with differing healthcare systems, 5 while the reasons for a delay in initiating DMARD therapy in RA patients appear to be both patient- and physician-dependent

Limit test studies failed to establish an LD50, indicating exceptionally low acute toxicity even at very high doses

On the other hand, the incidence of breast cancer in increasing, and breast cancer has become the leading cause of cancer-related death in females worldwide