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TSH: 0.45-4.5 U/ml

In horses that received the supplement, the researchers noticed an increased expression of mitophagy genes such as PINK1 and PARKIN

In one study suggesting a genetic link to poor ability to convert T4 to T3, a polymorphism in the DIO2 gene was found to be linked to who will or wont respond well to T4 therapy (due to how well their body converts T4 to T3)

doi: 10.1093/sxmrev/qeac003 30 GharibTMAbdel-AlIElatreisyAKandeelWEl-ShaerWAbdrabuhAMet al

Intramuscular hydroxocobalamin is the preferred treatment for most patients with confirmed deficiency, particularly when malabsorption is present or neurological symptoms exist