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Description

The DN-RAGE form has the extracellular (V- and C-type regions) and transmembrane domains like fl-RAGE, but lacks the intracellular cytoplasmic domain required for initiating downstream signaling

Disease-specific features are described across Alzheimers disease, Parkinsons disease, Multiple sclerosis, and Amyotrophic lateral sclerosis, emphasizing the distinct and overlapping pathways through which gut dysbiosis may contribute to pathogenesis

Association studies of several cholesterol-related genes (ABCA1, CETP and LIPC) with serum lipids and risk of Alzheimers disease

Acknowledgments The authors would like to thank Iran National Science Foundation (PN: 4004326) in providing scientific support to complete this project