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The honest, scientifically-grounded answer is this: the preclinical evidence is compelling and provides a strong rationale for further investigation

Restricting intake of potassium-rich fruits and vegetables inhibits the conversion of fermentable dietary fiber to SCFAs, leading to gut microbiota dysbiosis and increased intestinal protein fermentation, thereby increasing the formation of gut-derived uremic toxins (109)

Aberrant light cycles can modify gut microbiota composition, altering especially relative abundance of Lactobacillus and Bacteroidetes [348]