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These results show how misleading animal experimentation can be in terms of human health and emphasize the necessity to study the specific human disease in detail first and, on this basis, select the cost-appropriate, technologically advanced human-relevant model or method (e.g., use of isolated cells and tissues, organoids, robotics, computer bio-modeling) and system of testing before starting the research (312)

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Structural healing of tissues (tendons, ligaments) takes longer, with significant improvements visible on imaging at 4-6 weeks