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The Quinlan 2022 home-microneedling study in the Journal of Cosmetic Dermatology is the cleanest at-home efficacy signal in the literature: 11 women aged 33 to 61 received twice-daily topical growth factor serum plus twice-weekly microneedling at 0.2mm over three months
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In addition to recruiting TGF- in vivo , this peptide also overcomes the dilution problem of TGF-, where a controlled release system can be built by reserving TGF- in the scaffold using affinity peptides
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