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In summary, after consideration of the public comment we received, we are finalizing the APC assignments for CPT codes 36836 and 36837 without modification

The underlying mechanism of magnesiums effects lies in its important role in preventing central sensitization, which is considered to be the primary mechanism underlying FM

Although we performed multivariate adjustments, residual confounding may persist due to unmeasured factors such as dietary habits (e.g., irregular intake of animal-derived foods or B12-fortified products), unrecorded use of nutritional supplements, and genetic predispositionsparticularly MTHFR polymorphisms, which are known to influence homocysteine metabolism and folate cycling, thereby potentially altering the functional demand for vitamin B12

We also offer methylcobalamin (the bioactive form) upon special request after a quick consultation with our nursing staff

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