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It was first characterized by Predrag Sikiric and colleagues at the University of Zagreb in the early 1990s, and a 2025 literature and patent review cataloged its effects across gastrointestinal, musculoskeletal, and neural models

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More specifically, coffee includes these nutrients: Coffee beans are also rich in antioxidants, which are compounds that protect cells against damage

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Peptides as a Solution Peptides are small strings of amino acids that serve as bioactive agents in a number of bodily processes, including antioxidant protection