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18 The most bioavailable forms of B12 are methylcobalamin, hydroxocobalamin, and adenosylcobalamin

doi: 10.1111/jcmm.17200 123 YangZShiJChenLFuCShiDQuH

And, because the symptoms of STXBP1 overlap with a lot of other neurodevelopmental disorders (seizures, developmental delay, intellectual disability, motor issues, etc.), we can't use symptoms to accurately identify STXBP1 patients

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In vivo oral administration of AESN notably elevated antioxidant levels, reduced peripheral corneal vascularization and minimized structural damage, including corneal epithelial loss and iridocorneal angle narrowing