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RNA-seq reads were quantified using ikra v1.2.2 32 , an RNA-seq pipeline centered on Salmon 33 (accessed on April 30, 2020)

Urolithin A , a gut metabolite from pomegranate and berries sold as a mitophagy activator, has human trials showing improved muscle strength and mitochondrial markers in older adults, but the evidence is for muscle and metabolism, not the brain

Krediet E, Bostoen T, Breeksema J, van Schagen A, Passie T, Vermetten E

However, it is important to note that physical dependence alone does not indicate addiction

Our comprehensive approach includes counseling on diet, alcohol consumption, and maintaining a healthy weight