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In addition, continuous treatment of TQ (20 mg/kg/day, intraperitoneally, for 42 days) ameliorated D-Gal/AlCl 3 -induced cognitive deficit by protecting against oxidative stress, enhancing cholinergic function and increasing brain-derived neurotrophic factor (BDNF) and Bcl-2 levels [55]

Combined with adequate protein intake (widely recommended at 1.2-1.6g per kg of body weight during GLP-1 protocols) and resistance training, the higher dose ranges may actually preserve lean mass better than lower doses, because the energy deficit is being met predominantly through fat oxidation rather than muscle catabolism

Clin Chim Acta (1971) 31(1):1923

Although it is true that, when walking, one feels almost 4,000 meters above sea level