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For instance, Hemker 18 reported that conjugation of 2,6-dinitrophenol with a 4-isooctyl group increased the uncoupling activity by one order of magnitude

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This site has been the subject of intensive research in human, rat, and mouse models, as summarized in Table 1

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An J, Kim KW, Han S, Lee J, Lim YS

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Therefore, therapeutic strategies targeting intracellular regulatory environments may complement receptor-level interventions

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