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reported EGCG can induce transcriptomic program by increasing C-C motif chemokine ligand 5, cystatin 8, and interferon-induced transmembrane protein 3 characterized by reduced proliferative and stem-like features, which included the downregulation of Notch and CBFA2T3 pathways in macrophage-like differentiated human HL60 promyelocytic leukemia cells

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Under certain conditions, these DAMPs can trigger a robust immunogenic response, particularly when they are taken up by DCs, leading to enhanced antigen processing and cross-presentation, DC maturation, and the activation of tumor-specific CD8 + T cells

The full FMI report contains the complete reference list with primary research documentation