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The study established that FOXO4 maintains senescent cell viability by targeting p53 to the nucleus and preventing apoptosis, and that disrupting the FOXO4-p53 interaction with FOXO4-DRI causes p53 nuclear exclusion and cell-intrinsic apoptosis in ionising radiation-induced and doxorubicin-induced senescent IMR90 fibroblasts

22,28,29 This gated permeability and integrity of the claudin strands is largely reported to be sophisticatedly determined by the dynamic expression of pore-forming and siege-forming claudins (i.e., claudin-2 and claudin-4, respectively)

Since the 1960s, it has been reported causing damage to Zea mays and Sorghum bicolor globally

Xc- inhibitor sulfasalazine sensitizes colorectal cancer to cisplatin by a GSH-dependent mechanism

Excessive sweating can either be generalized or localized to specific parts of the body