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The treatment carries certain risks, such as allergic reactions, kidney or thyroid damage, infections, ochronosis, and toxicity

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Therefore, no SLC1A5 inhibitors with high specificity have been identified or designed, and SLC7A11 and GLUD inhibitors have not yet been applied to clinical oncology because of toxicity or efficacy as tool compounds [167, 170]

Immune factors do not act in isolation but form a vicious cycle with other characteristics of PCOS, such as insulin resistance and hyperandrogenism (20)

Thus a smaller pool of precursor cells or thinner myelin is then sufficient to fulfill the function of metabolic support and axonal transmission 60