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ShangCLiuZZhuYLuJGeCZhangCet alSARS-CoV-2 causes mitochondrial dysfunction and mitophagy impairment

Future Directions: Important future questions include the roles of other antioxidative systems in interacting with CAT and the ascorbateglutathione pathway as well as the nature and significance of processes that achieve redox exchange between different subcellular compartments

It is intended strictly for in-vitro laboratory research use only

Activation of this pathway increases the cells ability to neutralize ROS before they can damage proteins, lipids, or DNA

Following NO/ONOO - exposure, significant effects on cellular GSH metabolism are reported