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(3) direct targeting of fungal organelles, where AFPs were shown to target host cells and nuclei of susceptible fungi, as demonstrated by co-localization and DNA-binding assays 21

These patients, who collectively account for 25-30 percent of all people with major depression disorder, are precisely the ones most in need of effective pharmacological interventions, said Rasgon, who performed the bulk of the advanced data analysis for the study

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Western blotting showed that CBS level in the hippocampi was decreased by 63.2% in the D + ND group compared to that in the ND group, whereas it was increased by 152.4% in the D + MS group compared to that in the D + ND group (Fig