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doi: 10.1016/j.autrev.2020.102535 102 TsaiTGrotegutPReinehrSJoachimSC

By contrast, when applied at 500 M, a strong cell death was observed (18 1% of cell survival, n = 12)

The specific inhibitor of ferroptosis, Fer-1 promoted the osteoblast susceptibility to ferroptosis by elevating the expression of GPX4 and rescue their osteogenic function thus halting the progression of peri-prosthesis osteolysis