Additionally, in FDX1 knockout experiments, there was a significant decrease in protein lipoylation of DLAT and another TCA cycle component called dihydrolipoamide S-succinyltransferase (DLST), both of which no longer bound copper, suggesting the necessity of lipoyl moiety for copper binding
Metabonomics analysis of quercetin against the nephrotoxicity of acrylamide in rats
The XenoMouse strains were engineered with yeast artificial chromosomes (YACs) containing 245 kb and 190 kb-sized germline configuration fragments of the human heavy chain locus and kappa light chain locus, respectively, which contained core variable and constant region sequences
A subsequent study to understand the mechanism of action of DHS was carried out employing CHO cells as a cellular model (Table 2) [65]
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