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10.1021/acsnano.3c10674 [DOI] [PMC free article] [PubMed] [Google Scholar] Zhang H., Forman H

When the RAS protein binds to GTP in an activated state, the downstream Ras-Raf-MEK-ERK signaling pathway is abnormally activated, and excessive proliferation signals are transmitted, leading to uncontrolled cell proliferation and the development of tumors ( 3.5 Prostacyclin synthase (PTGIS) PTGIS is a member of the CYP8 family that catalyzes the conversion of prostaglandin H2 to prostacyclin I2 (PGI2) (Yu et al., 2017)

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Data were analysed from flow cytometry standard (FCS) files using FlowJo software

Remyelination does occur in adulthood 6,16,17,18,19 but the temporal interval within which the OLs receive crucial support in order to survive is restricted 20,21,22