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11 12 GLP-1s lower blood sugar, blood pressure, body weight, and inflammationall of which reduce strain on the heart and blood vessels 13 GLP-1 receptors are found in the heart and arteries, where they may also improve endothelial function, increase nitric oxide, and reduce oxidative stress, helping stabilize plaque and improve how the heart uses energy, especially during stress

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Pre-existing Peripheral Neuropathy Peripheral neuropathy damages the nerves, leading to weakness, numbness, and pain

Metabolism 44 : 1217 Hussain MA et al