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Court MH, Dua SX, von Moltke LL, Greenblatt DJ, Patten CJ, Miners JO, MacKenzie PI: Interindividual variability in acetaminophen glucuronidation by human liver microsomes: identification of relevant acetaminophen UDP-glucuronosyltransferase isoforms

Briefly, 1 10 4 cells were plated in white, opaque, 96 multi-well plates and, after 24 h, they were lysed by using either a total glutathione lysis reagent or an oxidized glutathione lysis reagent

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Absolute (water-referenced) Cr concentrations were determined by scaling the spectrum to the unsuppressed water peak, resulting in values with IU that approximate millimolar (mmol/l) concentrations