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Currently, the mainstream therapeutic armamentarium for IBD encompasses conventional agents (5-aminosalicylates, corticosteroids, and traditional immunosuppressants such as azathioprine), biologics, and small-molecule inhibitors, all of which have demonstrated efficacy in inducing and maintaining remission and in ameliorating symptomatic burden

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Using recommended doses minimizes risks

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Research has confirmed that hydroxysafflor yellow A (HSYA) can inhibit myocardial cell ferroptosis by activating HIF-1, which ultimately increases the expression of SLC7A11 and GPX4, thereby reducing myocardial ischemia/reperfusion injury in mice [49]