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Key questions remain regarding its ability to effectively inhibit NLRP3 inflammasome activation within the complex milieu of diabetic lung injury, and whether long-term suppression of this core innate immune pathway might lead to the activation of compensatory inflammatory pathways or other unknown off-target effects, all of which require longer-term clinical investigation

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Amphetamines do this too, but they also displace stored dopamine and norepinephrine, releasing even more into the synapse (Faraone SV, Neurosci Biobehav Rev 2018;87:255270)

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Indicated for patients targeting longevity, neurological performance, or recovery from metabolic decline