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The GSH and GSSG contents were analyzed after incubation for 0, 1, 2, 3, 4, 5, 6, 8, 10 and 12 h

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Iron toxicity and hepatic fibrogenesis Iron toxicity Abnormal iron homeostasis in HFE-hemochromatosis can lead to a wide variety of different iron-induced pathologies, including arthritis, cardiomyopathy, diabetes, cirrhosis, and HCC

Although they are not able to catalyze glutathione S -conjugation reactions at significant rates, they are considered to belong to the glutathione S -transferase (GST) superfamily (Dixon and Edwards, Glutathione peroxidase (GPX) Although GSSG could be generated as a product of GSH-dependent DHA reduction, genomics has revealed the complexity of the plant antioxidative system and identified several GSH-dependent enzymes that may play more direct roles in peroxide metabolism