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doi: 10.3390/diagnostics15010021 88 LiSZhugeAChenHHanSShenJWangKet al

Notably, type 2 diabetes mellitus (T2DM) accounts for more than 90% of all diabetes cases, a statistic that underscores its dominant position in the disease burden

The resulting anaerobic metabolism produces lactic acid and increased acidity (lower pH), which inhibits intramuscular calcium channels, weakening or even stopping contractions