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In 2018, a Biochemical Pharmacology study reported that membrane-permeable NNMT inhibitors given to obese mice cut white fat mass and body weight and shrank adipocytes [5]

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This decline is believed to contribute to many age-related health issues, including metabolic dysfunction, neurodegenerative diseases, and a general reduction in cellular resilience

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Thanks for sharing the information and the link to Dr Kivlahans article