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Description

The endogenous cannabinoid system controls extinction of aversive memories

doi: 10.3389/fnut.2022.854774 21 Evans-LackoS.Aguilar-GaxiolaS.Al-HamzawiA.AlonsoJ.BenjetC.BruffaertsR.et al

Methods: Using a physiologically-based pharmacokinetic (PBPK) model, we quantitatively compared the risk of CYP2C19-mediated DDIs in older adults taking S-CIT with any of four CYP2C19 inhibitors (omeprazole, esomeprazole, fluconazole, and fluoxetine)