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If you keep feeling tired or have other B12 deficiency symptoms, it might be time to check your treatment

Unlike vitamins or minerals, peptides are large, fragile molecules typically degraded in the digestive system before they can exert systemic effects

We believe including the reference product's data in the blended calculation for a biosimilar's payment limit in the limited circumstance described could be appropriate in determining an operationally reasonable payment limit because the FDA approval for the biosimilar relies in part on FDA's previous determination of safety, purity, and potency for the reference product, and the biosimilar is necessarily approved for at least one condition of use that has been previously approved for its reference product, as required under the 351(k) approval pathway

On August 13, 2025, CMS released updated CMS Medicare Part B vaccine payment allowance limits for the 2025 to 2026 influenza season, effective August 1, 2025, through July 31, 2026