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The ensuing chronic obstructive pulmonary pathology ultimately culminates in irreversible airflow obstruction, potentially escalating to chronic respiratory failure and mortality (205, 206)

School of Medicine, Southeast University, Nanjing 210096, China

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In addition, the inclusion of gp42 may have shielded the immune system from neutralizing epitopes on gH/gL that preferentially neutralize EBV infection of epithelial cells such as CL40

Decreased GSH leads to a cascade of events, including an inability to mitigate oxidative stress, a subsequent increase in the release of cytokines IL-6 and TGF-, both of which are shown to further decrease GSH synthesis, and an increase in platelet activation, contributing to microclot formation