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B12 then converts this methylmalonyl-CoA mutase into succinyl-CoA in a further step

Among the 77 infants tested at 6 weeks of age, the median blood vitamin B 12 level was 199 pmol/L (270 ng/L) in the supplemented group and 139 pmol/L (188 ng/L) in the placebo group.[23] Sixty-eight pregnant women in Bangladesh received 250 mcg oral vitamin B 12 capsules or placebo once daily beginning during their first trimester of pregnancy and continuing until 3 months postpartum

Further, the numbers were 35% from anti-estrogenic substances (tamoxifen, clomiphene, fulvestrant, toremifene, and raloxifene) and 20% from AIs (letrozole, anastrozole, exemestane, adrostatrienedione, and armistane) in 2022 (World Anti-Doping Agency, 2024b)