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The findings indicate that the onset of lipedema contributes to dysregulation of energy metabolism, involving changes in the metabolic pathways

10.1093/jn/134.3.489 53 ZhangJ

Achieving standardization across the entire workflow from sample collection and preservation to analytical determination constitutes a necessary prerequisite for translating metabolomic research findings into clinical diagnostic and therapeutic decision-making tools

Cagrilintide was designed by making structural modifications to amylin to improve its potency, solubility and duration of action, as well as reducing its propensity to form amyloid fibrils (71)