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Next, the left ventricle was perfused ex vivo using EDTA buffer, which was replaced with perfusion buffer when the thrombus was completely removed

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In the absence of reduced glutathione (e.g., due to G6PD deficiency), RBCs become susceptible to oxidative stress that can damage erythrocyte membranes, resulting in intravascular and extravascular hemolysis

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10.1007/s00280-013-2320-9 Cancer Chemother

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As mentioned above, the PLs peroxidation of membrane can lead to the leakage of cellular contents, and the release of DAMPs will further initiate other cell death ways

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