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In the past twenty years, and mainly by repurposing drugs use, molecules have been identified but to date, clinical trials display moderated efficiency

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doi: 10.1371/journal.ppat.1008376, 97 Van De WijgertJ.VerwijsM

This is where the popular version of the argument breaks down, so it is worth stating the trap plainly

"[Associations between insulin resistance and three B-vitamins in European adolescents: the HELENA study]"