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Moreover, as reported in a previous study 11,12 , ferroptotic cell death is capable of releasing its intracellular components as pro-inflammatory damage-associated molecular patterns (DAMPs), and the releasing and accumulation of DAMPs can trigger tissue inflammation, resulting in the development of various inflammatory diseases (e.g., PE 12 )

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In particular, high glucose or palmitate induce islet cell cytokine secretion and promote the migration of monocytes and neutrophils

It is also explored by patients who suffer from gastrointestinal problems such as inflammatory bowel disease (IBD), ulcers, or leaky gut syndrome, as it may help repair the gut lining and reduce inflammation in the digestive system