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Description

To investigate the tissue-specific effects of MT1-MMP deficiency on insulin sensitivity, we performed hyperinsulinemic/euglycemic clamp studies in WT and Mmp14 +/ mice on high-fat diet

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Interestingly, the chip was also exploited with ShwachmanDiamond syndrome (SDS) patient cells, a genetic bone marrow failure syndrome characterized by biallelic mutations in the SBDS gene