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Description

During embryonic development, skeletal muscle is formed following progenitor cell commitment to myogenic lineage, founding the myoblast and subsequent development of the myocyte, and the details of this process in relation to androgens and AR are reviewed elsewhere [99]

Astrocytes release free fatty acids (FFAs) from lipid droplets, and the released fatty acids enter the mitochondria and bind to carnitine to form LCACs, the accumulation of which leads to mitochondrial dysfunction in astrocytes and exacerbates neuronal damage [115]

Additionally, in the CRC incidence analysis, the concentration of acetate was significantly higher in healthy controls than in CRC patients, with a SMD of 0.61 (95% CI: 0.091.13, p = 0.02) (Alvandi et al., 2022)