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Beyond solid tumors, leukemic cells display dysregulated iron metabolism, leading to iron overload and increased ROS production, which in turn disrupt normal hematopoietic stem cell (HSC) functions like self-renewal, differentiation and quiescence (128,129)

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[PubMed] [Google Scholar] [48].Tong J, Li D, Meng H, et al

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Rising atmospheric CO 2 and human nutrition: toward globally imbalanced plant stoichiometry

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4g and Supplementary Fig

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