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At the same time, alcohol depletes glutathione

Collectively, these findings support the role of fecal microbiota influences and metabolic pathways (oxidative stress, inflammation) as underlying mechanisms for the beneficial effects of the MD in reproductive health, highlighting microbiota manipulation and metabolic interventions as promising avenues for further exploration (72)

J Exp Med 1984

Inhibiting SHP2 reduces glycolysis, promotes microglial M1 polarization, and alleviates secondary inflammation following spinal cord injury in a mouse model