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Supplementary material The Supplementary Material for this article can be found online at: SUPPLEMENTARY FIGURE 1 Refusing the role of intraperitoneal solvent volume on neuropathic pain after CCI

Notably, schlank, the drosophila CERS isoform, and mammalian CERS2 are capable of responding to intracellular fatty acid levels with direct binding and upregulation of Srebf expression and, conversely, downregulated expression of intracellular lipases (74, 75)

Similarly, synergistic activity was observed between DEM and fluazinam, which has the same MoA with SYP-14288, and the SR value was highest at 40.50 in a 1:80 weight ratio

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Conclusion: SYNE1 genetic variants are associated with a spectrum of neurological disorders, particularly SYNE1 ataxia, which presents with both cerebellar and noncerebellar symptoms