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doi: 10.1111/1751-2980.13203 Pubmed Abstract CrossRef Google Scholar View reference in article 34 ChogleAEl-ChammasKSantucciNGrimmMDorfmanLGrahamK

Sulfation and oxidation increased, while glucuronidation decreased following excessive administration of APAP (6.0 mM/h)

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A recent clinical trial examining the hepcidin mimetic, Rusfertide (PTG-300), for use in hereditary hemochromatosis demonstrated reduction in both transferrin saturation and serum iron during treatment, reduced requirement for phlebotomy during the study period, and resulted in control of hepatic iron concentration [163]