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This apparent discrepancy is actually consistent with a massive body of literature from psychology and neuroscience that human feelings (including symptoms) are not flawless reflections of peripheral sensory input but instead feelings are a loose interpretation or prediction merely tailored by peripheral sensory input (Kleckner and Quigley, 2015

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However, caution is warranted, as this study was conducted in mice and relied on oral administration of L-carnitine, which limits extrapolation

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For longitudinal peak systolic strain measurements, the median inter-observer ICC was 0.74 [0.560.85] and intra-observer ICC was 0.74 [0.560.79]

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