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de Rothschild, Paris, France, 10 Neurology Department, Hpital Lariboisire, Paris, France, 11 Universit Paris Cit, Paris, France, 12 INSERM, U1144, Paris, France, 13 FHU NeuroVasc, Paris, France, 14 Department of Neurology, Foch Hospital, Versailles Saint-Quentin en Yvelines University, Suresnes, France, 15 Department of Diagnostic and Therapeutic Neuroradiology, Universit de Lorraine, CHRU-Nancy, Nancy, France, 16 Universit de Lorraine, INSERM 1254, IADI, Nancy, France Background and Aims: Time from symptom onset to puncture (TSOP) and time from puncture to reperfusion (TPTR) are associated with worse outcome in ischemic stroke patients treated with endovascular therapy (EVT) in the early window ( 6 h), where EVT may benefit patients with favorable imaging profiles is unknown (late window paradox)

Agents targeting bile acid homeostasis Dysregulated bile acid metabolism contributes to liver injury and disrupts lipid homeostasis, correlating with disease severity in SAH

Inhibitory effect of silver diamine fluoride on dentine demineralisation and collagen degradation

55 Hormonal factors Hormonal factors like long-term exposure to estrogen 56 and reproductive history influenced by factors such as late menopause, 57 early menarche for every year younger at menarche, 58 nulliparity, 59 and abortion 60 exhibit a connection to an elevated vulnerability to breast cancer

We will move from general information to practical decision-support, emphasizing that while B12 is largely very safe, a personalized, informed approach is always the wisest path