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*Correspondence: Gina Chapa-Koloffon [email protected] These authors have contributed equally to this work and share first authorship This article was submitted to Molecular Psychiatry, a section of the journal Frontiers in Psychiatry Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

Large-scale, long-term follow-up (including open-label extensions and real-world registries) is needed to monitor rebound weight gain after stopping therapy, as early reports suggest weight tends to increase once medication is discontinued (43)

10.1016/j.reprotox.2012.09.005 74 GuibertS.FornT.WeberM

The goal is to help patients remain on an effective therapy long enough to achieve sustained metabolic and cardiovascular benefit without unnecessary interruption

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