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(132) demonstrated that pregnanolone hemisuccinate (PAHS) inhibits NMDA-induced currents and cell death in primary cultures of hippocampal neurons

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Glossary AD Alzheimers Disease NFTs Neurofibrillary Tangles Ab Amyloid-beta SIRT1 Sirtuin 1 ANK1 Ankyrin 1 RPL13 Ribosomal Protein L13 RHBDF2 Rhomboids Family Member 2 CDH23 Cadherin 23 5mC 5-Methylcytosine 5hmC 5-Hydroxymethylcytosine APP Amyloid Precursor Protein Dnmt3a DNA Methyltransferase 3A Tet2 Ten-Eleven Translocation2 ATP6V1G2 ATPase H+ Transporting V1 Subunit G2 VCP ValosinContaining Protein TMEM39A Transmembrane Protein 39A TNXB Tenascin XB ROS Reactive Oxygen Species OH Hydroxyl Radicals