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Epigenetics derives its root from the Greek prefix epi meaning above or over, and when linked with genetics, epigenetics literally translates to on top of genetics, alluding to an added layer of heritable characteristics in addition to genetic inheritance

doi: 10.1016/j.celrep.2021.109228 151 HuangM.MalovicE.EalyA.JinH.AnantharamV.KanthasamyA.et al

Shpakov A, Chistyakova O, Derkach K, Bondareva V

In particular, in 43 septic patients with MAS and concomitant disseminated intravascular coagulation, hepatobiliary dysfunction, cytopenias and hyperferritinemia, when compared with placebo, anakinra treatment significantly improved the28-day survival rate (anakinra: 65.4%

This algorithm has been incorporated into the NBLAST and XBLAST programs of Altschul et al (1990, J.mol.biol.215: 403-