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Dihydroflavone Hesperidin reduces the infiltration of inflammatory cells and the production of proinflammatory cytokines, blocks the activation of Toll-like receptor (TLR)-4 signaling, and reduces oxidative stress and inflammatory response induced by APAP in mice

Redox reactions are integral to cell signaling, regulating a variety of biological processes including cell proliferation, differentiation, and apoptosis [2]

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J Biol Chem 279:1624616253

10.1016/j.biomaterials.2010.03.067 109