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Six Phase I/II clinical trials enrolling approximately 900 participants confirmed an excellent safety profile with no serious adverse events attributed to the compound

The hormonal changes affect the way fluid is stored in the body, often causing bloating in the stomach and abdomen

They might also apply pressure to the suspected muscle knot to see if it causes referred pain (pain in another area of the body)

AOD9604, on the other hand, hasnt demonstrated the same level of statistically significant outcomes in humans (trial overview)

The mechanism appears to involve changes in how skin bacteria produce porphyrins, compounds that can promote inflammation within hair follicles