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Evidence Integration Overall, considering the available evidence from human, animal, and mechanistic studies, evidence indicates that exposure to jet fuels is likely to cause neurotoxicity in humans under relevant exposure circumstances (Table 1 and Supplemental Digital Content, Supplementary Table S9, This conclusion is based primarily on evidence of hearing impairment or abnormal auditory processing in both epidemiologic and animal toxicological studies

Ann Afr Med

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In addition, it also showed therapeutic benefits in various animal disease models, including cardiovascular disorders (Silva et al., 2016)

However, the implication for neuroprotection in specific brain regions is not known