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The main characteristics of chronic kidney disease (CKD) include progressive renal tissue structural lesions and impaired renal excretory function, which may be due to functional nephron defects caused by diverse causative variables, including diabetes, interstitial nephritis, glomerulonephritis, obstructive nephropathy and polycystic kidney disease (116)

UNC0638 is a further synthetic compound based on UNC0224 and UNC0321 that significantly downregulates H3K9me2 in a variety of cells

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Identification of novel somatic TP53 mutations in patients with high-grade serous ovarian cancer (HGSOC) using next-generation sequencing (NGS)